When planning a trip abroad, especially to tropical or subtropical regions, it’s essential to think beyond your itinerary and consider how to protect your health while away. At Edinburgh Travel Clinic, we regularly advise travellers on both vaccinations and insect spray—two vital tools in preventing serious illnesses caused by insect bites.
While many people assume that vaccines alone offer enough protection, the reality is that vaccinations and insect spray work best together, targeting different threats and helping you stay safe no matter where your travels take you.
Here’s why both are crucial and how they complement each other.
Understanding the Difference
Vaccinations are designed to build long-term immunity to specific diseases. You typically receive a vaccine days or weeks before travel, giving your immune system time to respond. Vaccines are especially effective against viral or bacterial infections, some of which are spread by insects.
On the other hand, insect spray is a physical barrier. It provides immediate protection by deterring insects—primarily mosquitoes, but also ticks, midges, and sandflies—from biting you in the first place. It doesn’t immunise you, but it can prevent exposure to a variety of insect-borne illnesses, including many that do not yet have vaccines.

Insect-Borne Diseases with Available Vaccines
There are several diseases spread by insect bites for which vaccines exist. If you’re travelling to at-risk areas, these may be recommended:
1. Yellow Fever
Spread by: Aedes mosquitoes
Vaccine: A highly effective single-dose vaccine is available and often required for entry to certain countries in Africa and South America.
Insect spray still essential to avoid other mosquito-borne infections.
2. Japanese Encephalitis
Spread by: Culex mosquitoes
Vaccine: Recommended for long stays or rural travel in parts of Asia.
Insect spray should still be used, especially in the evenings when these mosquitoes are active.
3. Tick-Borne Encephalitis (TBE)
Spread by: Infected ticks
Vaccine: Available and advised for rural travellers in parts of Central and Eastern Europe.
Insect repellent helps protect against both ticks and mosquitoes.
Insect-Borne Diseases Without Vaccines
Many common travel-related infections have no vaccine available, making insect spray your only line of defence:
1. Dengue Fever
Spread by: Aedes mosquitoes (daytime biters)
Found in: Asia, South America, Central America, Africa, and parts of the Caribbean
Prevention: Use insect spray consistently during the day, wear long sleeves, and stay in screened or air-conditioned accommodation.
2. Zika Virus
Spread by: Aedes mosquitoes
Risks: Especially dangerous for pregnant women due to birth defect risks.
Prevention: Avoid bites through insect spray and protective clothing.
3. Chikungunya
Spread by: Aedes mosquitoes
Symptoms: Fever, joint pain, and fatigue
No vaccine: Insect repellent is the primary protection.
4. Malaria
Spread by: Anopheles mosquitoes (night-time biters)
Prevention: While there is no vaccine widely available for travellers, antimalarial tablets are often prescribed.
Insect spray is vital, especially in the evenings and at night.

Why You Need Both
Even if you’re vaccinated, the areas where insect-borne diseases are prevalent often pose multiple risks. For example, a traveller to West Africa may be vaccinated against Yellow Fever but could still be exposed to malaria and dengue. Without an effective insect spray, they remain vulnerable.
Insect repellent enhances the protection that vaccines can’t offer. It’s particularly important because:
Vaccines don’t protect against every insect-borne illness.
Some vaccines take time to become effective.
No vaccine offers 100% protection.
Insect spray also protects against bites that can cause skin infections and allergic reactions.
Choosing the Right Insect Spray
At Edinburgh Travel Clinic, we recommend using insect sprays that contain:
DEET (20–50%): The gold standard for mosquito and tick repellents.
Picaridin/Icaridin: A good alternative for those with sensitivity to DEET.
Oil of Lemon Eucalyptus: A natural option, though often less long-lasting.
Apply insect spray to all exposed skin and reapply according to the product’s instructions—especially after swimming or sweating.
Get Protected with Edinburgh Travel Clinic
Protecting yourself from insect-borne diseases requires a combination of smart planning and the right tools. Vaccinations prepare your immune system, while insect spray offers immediate, on-the-ground protection.
When you book your appointment with us, we’ll help you create a personalised travel health plan based on your destination, duration, and activities. This includes recommended vaccines, advice on insect spray use, antimalarial medication if needed, and other essential precautions. Contact us to learn more.
Travel confidently—book your pre-travel consultation at Edinburgh Travel Clinic today and stay protected wherever you go.
This blog was written on behalf of Edinburgh Travel Clinic by Pharmacy Mentor.
